People

Dr Antonella Trotta

Senior Lecturer
School of Health and Social Care
Dr Antonella Trotta

Profile

Biography

I trained as Clinical Psychologist at the Department of Experimental Biomedicine and Clinical Neuroscience, University of Palermo, Italy. For my doctorate (2012-2015) at the Institute of Psychiatry, Psychology & Neuroscience (IoPPN), King’s College London, I focused on the interaction between genetic vulnerabilities and childhood adversities in first episode psychosis I have received a number of recognitions for the international quality of my research work, including young investigator travel awards to attend the Schizophrenia International Research Society conference (2012, 2014 and 2016) and the International Congress on Schizophrenia Research (2013, 2017). Additionally, in 2014, I was awarded a King’s Partnership Grant, in collaboration with the University of Hong Kong, to conduct the first study applying a polygenic GxE interaction approach in psychosis. For my post-doctoral fellowships, I has been investigating developmental risk factors for adult psychopathology using a longitudinal twin cohort study of 2,232 British children (E-Risk Longitudinal Twin Study). My clinical and research interests also focus on psychological mechanisms, such as affective regulation and cognition, through which childhood adversity contributes to the onset and outcomes of severe mental illnesses, to inform the development of trauma informed psychological treatment for young adults.

Qualifications

  • PhD in Psychosis Studies King's College London, (2015)

  • DClinPsy Universita' di Palermo, (2010)

  • PGDip University of Essex, (2014)

Appointments

University of Essex

  • Senior Lecturer, School of Health and Social Care, Essex University (25/10/2021 - present)

Other academic

  • Clinical Reseach Fellow, King's College London (1/9/2017 - 31/12/2019)

  • Honorary Lecturer, King's College London (1/1/2017 - present)

Research and professional activities

Research interests

Psychobiological pathways from childhood adversity to severe mental illnesses

Key words: childhood trauma
Open to supervise

Psychoanalytic Psychotherapy

Key words: Psychoanalysis
Open to supervise

Conferences and presentations

The effectiveness of psychoanalytic psychotherapy for young adults: a systematic review and meta-analysis

International Psychoanalytical Association 52nd Congress, 1/7/2021

Associations between childhood victimization, inflammatory biomarkers and psychotic phenomena in childhood and adolescence: a longitudinal cohort study ​

British Association of Psyhopharmacology Summer meeting, 1/6/2021

The impact of Childhood maltreatment on the child's mind

Invited presentation, Keynote presentation, Prochild Winter School, Prochild Winter School, Bologna, Italy, 25/1/2021

Teaching and supervision

Current teaching responsibilities

  • Clinical Applications 1 (HS762)

  • Clinical Research 1 (HS763)

  • Clinical Interventions and Skills 1 (HS765)

  • Clinical Research 2 (HS773)

  • Personal and Professional Development 3 (HS784)

Publications

Journal articles (40)

Yiend, J., Lam, CLM., Schmidt, N., Crane, B., Heslin, M., Kabir, T., McGuire, P., Meek, C., Mouchlianitis, E., Peters, E., Stahl, D., Trotta, A. and Shergill, S., Cognitive bias modification for paranoia (CBM-pa): a randomised controlled feasibility study in patients with distressing paranoid beliefs. Psychological Medicine, 1-13

Leung, CJ., Yiend, J., Trotta, A. and Lee, TMC., (2022). The combined cognitive bias hypothesis in anxiety: A systematic review and meta-analysis. Journal of Anxiety Disorders. 89, 102575-102575

Aas, M., Alameda, L., Di Forti, M., Quattrone, D., Dazzan, P., Trotta, A., Ferraro, L., Rodriguez, V., Vassos, E., Sham, P., Tripoli, G., Cascia, CL., Barbera, DL., Tarricone, I., Muratori, R., Berardi, D., Lasalvia, A., Tosato, S., Szöke, A., Llorca, P-M., Arango, C., Tortelli, A., de Haan, L., Velthorst, E., Bobes, J., Bernardo, M., Sanjuán, J., Santos, JL., Arrojo, M., Del-Ben, CM., Menezes, PR., Selten, J-P., Jones, PB., Jongsma, HE., Kirkbride, JB., Rutten, BPF., van Os, J., Gayer-Anderson, C., Murray, RM. and Morgan, C., (2021). Synergistic effects of childhood adversity and polygenic risk in first-episode psychosis: the EU-GEI study. Psychological Medicine, 1-9

Trotta, A., Kang, J., Stahl, D. and Yiend, J., (2021). Interpretation Bias in Paranoia: A Systematic Review and Meta-Analysis. Clinical Psychological Science. 9 (1), 3-23

Trotta, A., Arseneault, L., Danese, A., Mondelli, V., Rasmussen, LJH. and Fisher, HL., (2021). Associations between childhood victimization, inflammatory biomarkers and psychotic phenomena in adolescence: A longitudinal cohort study.. Brain, Behavior, and Immunity. 98, 74-85

Ajnakina, O., Agbedjro, D., Lally, J., Forti, MD., Trotta, A., Mondelli, V., Pariante, C., Dazzan, P., Gaughran, F., Fisher, HL., David, A., Murray, RM. and Stahl, D., (2020). Predicting onset of early- and late-treatment resistance in first-episode schizophrenia patients using advanced shrinkage statistical methods in a small sample. Psychiatry Research. 294, 113527-113527

Murray, RM., Mondelli, V., Stilo, SA., Trotta, A., Sideli, L., Ajnakina, O., Ferraro, L., Vassos, E., Iyegbe, C., Schoeler, T., Bhattacharyya, S., Marques, TR., Dazzan, P., Lopez-Morinigo, J., Colizzi, M., O'Connor, J., Falcone, MA., Quattrone, D., Rodriguez, V., Tripoli, G., La Barbera, D., La Cascia, C., Alameda, L., Trotta, G., Morgan, C., Gaughran, F., David, A. and Di Forti, M., (2020). The influence of risk factors on the onset and outcome of psychosis: What we learned from the GAP study. Schizophrenia Research. 225, 63-68

Vassos, E., Sham, P., Kempton, M., Trotta, A., Stilo, SA., Gayer-Anderson, C., Di Forti, M., Lewis, CM., Murray, RM. and Morgan, C., (2020). The Maudsley environmental risk score for psychosis. Psychological Medicine. 50 (13), 2213-2220

Sideli, L., Murray, RM., Schimmenti, A., Corso, M., La Barbera, D., Trotta, A. and Fisher, HL., (2020). Childhood adversity and psychosis: a systematic review of bio-psycho-social mediators and moderators. Psychological Medicine. 50 (11), 1761-1782

Trotta, A., Arseneault, L., Caspi, A., Moffitt, TE., Danese, A., Pariante, C. and Fisher, HL., (2020). Mental Health and Functional Outcomes in Young Adulthood of Children With Psychotic Symptoms: A Longitudinal Cohort Study. Schizophrenia Bulletin. 46 (2), 261-271

Trotta, A., Iyegbe, C., Yiend, J., Dazzan, P., David, AS., Pariante, C., Mondelli, V., Colizzi, M., Murray, RM., Di Forti, M. and Fisher, HL., (2019). Interaction between childhood adversity and functional polymorphisms in the dopamine pathway on first-episode psychosis. Schizophrenia Research. 205, 51-57

Leung, CJ., Fosuaah, A., Frerichs, J., Heslin, M., Kabir, T., Lee, TMC., McGuire, P., Meek, C., Mouchlianitis, E., Nath, AS., Peters, E., Shergill, S., Stahl, D., Trotta, A. and Yiend, J., (2019). A qualitative study of the acceptability of cognitive bias modification for paranoia (CBM-pa) in patients with psychosis. BMC Psychiatry. 19 (1), 225-

Rodriguez, V., Ajnakina, O., Stilo, SA., Mondelli, V., Marques, TR., Trotta, A., Quattrone, D., Gardner-Sood, P., Colizzi, M., Wiffen, BD., Dazzan, P., Di Forti, M., Falcone, MA., David, AS. and Murray, RM., (2019). Jumping to conclusions at first onset of psychosis predicts longer admissions, more compulsory admissions and police involvement over the next 4 years: the GAP study. Psychological Medicine. 49 (13), 2256-2266

Ajnakina, O., Trotta, A., Di Forti, M., Stilo, S., Kolliakou, A., Gardner-Sood, P., Lopez-Morinigo, J-D., Gaughran, F., David, A., Dazzan, P., Pariante, C., Mondelli, V., Murray, R. and Fisher, H., (2018). T130. ASSOCIATIONS BETWEEN DIFFERENT TYPES OF CHILDHOOD ADVERSITY AND 5-YEAR OUTCOMES IN FIRST-EPISODE PSYCHOSIS PATIENTS. Schizophrenia Bulletin. 44 (suppl_1), S166-S166

Rodriguez, V., Ajnakina, O., Stilo, S., Mondelli, V., Marques, TR., Trotta, A., Tripoli, G., Quattrone, D., Colizzi, M., Sood, P., Wiffen, B., Dazzan, P., Vassos, E., Forti, MD., David, A. and Murray, R., (2018). F68. PREMORBID IQ, EDUCATIONAL LEVEL AND JUMPING TO CONCLUSIONS AS PREDICTORS OF CLINICAL OUTCOME AT FIRST ONSET OF PSYCHOSIS OVER THE NEXT 4 YEARS: THE GAP STUDY. Schizophrenia Bulletin. 44 (suppl_1), S246-S246

Ajnakina, O., Trotta, A., Forti, MD., Stilo, SA., Kolliakou, A., Gardner-Sood, P., Lopez-Morinigo, J., Gaughran, F., David, AS., Dazzan, P., Pariante, C., Mondelli, V., Murray, RM. and Fisher, HL., (2018). Different types of childhood adversity and 5-year outcomes in a longitudinal cohort of first-episode psychosis patients. Psychiatry Research. 269, 199-206

Murray, R., Forti, MD., Vassos, E., Trotta, A., Quigley, H., Ajnakina, O., Quattrone, D., Tripoli, G., Rodriguez, V. and Morgan, C., (2018). 35.4 A PUBLIC HEALTH APPROACH TO THE PREVENTION OF PSYCHOSIS. Schizophrenia Bulletin. 44 (suppl_1), S59-S59

Trotta, A., Arseneault, L., Caspi, A., Danese, A., Moffitt, T., Pariante, C. and Fisher, H., (2018). O8.3. CLINICAL AND FUNCTIONAL OUTCOMES IN YOUNG ADULTHOOD OF CHILDREN WITH PSYCHOTIC SYMPTOMS: A LONGITUDINAL TWIN COHORT STUDY. Schizophrenia Bulletin. 44 (suppl_1), S97-S97

Rodriguez, V., Ajnakina, O., Stilo, S., Mondelli, V., Marques, TR., Trotta, A., Tripoli, G., Quattrone, D., Colizzi, M., Sood, P., Wiffen, B., Dazzan, P., Vassos, E., Forti, MD., David, A. and Murray, R., (2018). F68. PREMORBID IQ, EDUCATIONAL LEVEL AND JUMPING TO CONCLUSIONS AS PREDICTORS OF CLINICAL OUTCOME AT FIRST ONSET OF PSYCHOSIS OVER THE NEXT 4 YEARS: THE GAP STUDY. Schizophrenia bulletin. 44 (Suppl 1), S246-S246

Murray, R., Forti, MD., Vassos, E., Trotta, A., Quigley, H., Ajnakina, O., Quattrone, D., Tripoli, G., Rodriguez, V. and Morgan, C., (2018). 35.4 A PUBLIC HEALTH APPROACH TO THE PREVENTION OF PSYCHOSIS. Schizophrenia bulletin. 44 (Suppl 1), S59-S59

Trotta, A., Arseneault, L., Caspi, A., Danese, A., Moffitt, T., Pariante, C. and Fisher, H., (2018). O8.3. CLINICAL AND FUNCTIONAL OUTCOMES IN YOUNG ADULTHOOD OF CHILDREN WITH PSYCHOTIC SYMPTOMS: A LONGITUDINAL TWIN COHORT STUDY. Schizophrenia bulletin. 44 (Suppl 1), S97-S97

Ajnakina, O., Trotta, A., Di Forti, M., Stilo, S., Kolliakou, A., Gardner-Sood, P., Lopez-Morinigo, J-D., Gaughran, F., David, A., Dazzan, P., Pariante, C., Mondelli, V., Murray, R. and Fisher, H., (2018). T130. ASSOCIATIONS BETWEEN DIFFERENT TYPES OF CHILDHOOD ADVERSITY AND 5-YEAR OUTCOMES IN FIRST-EPISODE PSYCHOSIS PATIENTS. Schizophrenia bulletin. 44 (Suppl 1), S166-S166

Trotta, A. and Formica, I., (2018). The Oedipus complex in psychoanalysis: Reflections on Freud's clinical cases. Mediterranean Journal of Clinical Psychology. 6 (1), 1-17

Yiend, J., Trotta, A., Meek, C., Dzafic, I., Baldus, N., Crane, B., Kabir, T., Stahl, D., Heslin, M., Shergill, S., McGuire, P. and Peters, E., (2017). Cognitive Bias Modification for paranoia (CBM-pa): study protocol for a randomised controlled trial. Trials. 18 (1), 298-

Trotta, A., Iyegbe, C., Di Forti, M., Sham, PC., Campbell, DD., Cherny, S., Mondelli, V., Aitchison, K., Murray, R., Vassos, E. and Fisher, H., (2017). 133. Interplay Between Schizophrenia Polygenic Risk Score and Childhood Adversity in First-Presentation Psychotic Disorder: A Pilot Study. Schizophrenia Bulletin. 43 (suppl_1), S72-S72

O’Connor, JA., Ellett, L., Ajnakina, O., Schoeler, T., Kollliakou, A., Trotta, A., Wiffen, BD., Falcone, AM., Di Forti, M., Murray, RM., Bhattacharyya, S. and David, AS., (2017). Can cognitive insight predict symptom remission in a first episode psychosis cohort?. BMC Psychiatry. 17 (1), 54-

Trotta, A., Iyegbe, C., Di Forti, M., Sham, PC., Campbell, DD., Cherny, S., Mondelli, V., Aitchison, K., Murray, R., Vassos, E. and Fisher, H., (2017). 133. Interplay Between Schizophrenia Polygenic Risk Score and Childhood Adversity in First-Presentation Psychotic Disorder: A Pilot Study. Schizophrenia bulletin. 43 (Suppl 1), S72-S72

Lally, J., Ajnakina, O., Di Forti, M., Trotta, A., Demjaha, A., Kolliakou, A., Mondelli, V., Reis Marques, T., Pariante, C., Dazzan, P., Shergil, SS., Howes, OD., David, AS., MacCabe, JH., Gaughran, F. and Murray, RM., (2016). Two distinct patterns of treatment resistance: clinical predictors of treatment resistance in first-episode schizophrenia spectrum psychoses. Psychological Medicine. 46 (15), 3231-3240

Trotta, A., Murray, RM., David, AS., Kolliakou, A., O’Connor, J., Di Forti, M., Dazzan, P., Mondelli, V., Morgan, C. and Fisher, HL., (2016). Impact of Different Childhood Adversities on 1-Year Outcomes of Psychotic Disorder in the Genetics and Psychosis Study. Schizophrenia Bulletin. 42 (2), 464-475

Colizzi, M., Carra, E., Fraietta, S., Lally, J., Quattrone, D., Bonaccorso, S., Mondelli, V., Ajnakina, O., Dazzan, P., Trotta, A., Sideli, L., Kolliakou, A., Gaughran, F., Khondoker, M., David, AS., Murray, RM., MacCabe, JH. and Di Forti, M., (2016). Substance use, medication adherence and outcome one year following a first episode of psychosis. Schizophrenia Research. 170 (2-3), 311-317

Ajnakina, O., Trotta, A., Oakley-Hannibal, E., Di Forti, M., Stilo, SA., Kolliakou, A., Gardner-Sood, P., Gaughran, F., David, AS., Dazzan, P., Pariante, C., Mondelli, V., Morgan, C., Vassos, E., Murray, RM. and Fisher, HL., (2016). Impact of childhood adversities on specific symptom dimensions in first-episode psychosis. Psychological Medicine. 46 (2), 317-326

Trotta, A., Iyegbe, C., Di Forti, M., Sham, PC., Campbell, DD., Cherny, SS., Mondelli, V., Aitchison, KJ., Murray, RM., Vassos, E. and Fisher, HL., (2016). Interplay between Schizophrenia Polygenic Risk Score and Childhood Adversity in First-Presentation Psychotic Disorder: A Pilot Study. PLOS ONE. 11 (9), e0163319-e0163319

Di Forti, M., Marconi, A., Carra, E., Fraietta, S., Trotta, A., Bonomo, M., Bianconi, F., Gardner-Sood, P., O'Connor, J., Russo, M., Stilo, SA., Marques, TR., Mondelli, V., Dazzan, P., Pariante, C., David, AS., Gaughran, F., Atakan, Z., Iyegbe, C., Powell, J., Morgan, C., Lynskey, M. and Murray, RM., (2015). Proportion of patients in south London with first-episode psychosis attributable to use of high potency cannabis: a case-control study. The Lancet Psychiatry. 2 (3), 233-238

Trotta, A., Forti, MD., lyegbe, C., Green, P., Dazzan, P., Mondelli, V., Morgan, C., Murray, RM. and Fisher, HL., (2015). Familial risk and childhood adversity interplay in the onset of psychosis. BJPsych Open. 1 (1), 6-13

Trotta, A., Murray, RM. and Fisher, HL., (2015). The impact of childhood adversity on the persistence of psychotic symptoms: a systematic review and meta-analysis. Psychological Medicine. 45 (12), 2481-2498

Trotta, A., Murray, RM. and MacCabe, JH., (2015). Do premorbid and post-onset cognitive functioning differ between schizophrenia and bipolar disorder? A systematic review and meta-analysis. Psychological Medicine. 45 (2), 381-394

Di Forti, M., Sallis, H., Allegri, F., Trotta, A., Ferraro, L., Stilo, SA., Marconi, A., La Cascia, C., Reis Marques, T., Pariante, C., Dazzan, P., Mondelli, V., Paparelli, A., Kolliakou, A., Prata, D., Gaughran, F., David, AS., Morgan, C., Stahl, D., Khondoker, M., MacCabe, JH. and Murray, RM., (2014). Daily Use, Especially of High-Potency Cannabis, Drives the Earlier Onset of Psychosis in Cannabis Users. Schizophrenia Bulletin. 40 (6), 1509-1517

Ferraro, L., Russo, M., O'Connor, J., Wiffen, BDR., Falcone, MA., Sideli, L., Gardner-Sood, P., Stilo, S., Trotta, A., Dazzan, P., Mondelli, V., Taylor, H., Friedman, B., Sallis, H., La Cascia, C., La Barbera, D., David, AS., Reichenberg, A., Murray, RM. and Di Forti, M., (2013). Cannabis users have higher premorbid IQ than other patients with first onset psychosis. Schizophrenia Research. 150 (1), 129-135

Trotta, A., Di Forti, M., Mondelli, V., Dazzan, P., Pariante, C., David, A., Mulè, A., Ferraro, L., Formica, I., Murray, RM. and Fisher, HL., (2013). Prevalence of bullying victimisation amongst first-episode psychosis patients and unaffected controls. Schizophrenia Research. 150 (1), 169-175

Abbs, B., Achalia, RM., Adelufosi, AO., Aktener, AY., Beveridge, NJ., Bhakta, SG., Blackman, RK., Bora, E., Byun, MS., Cabanis, M., Carrion, R., Castellani, CA., Chow, TJ., Dmitrzak-Weglarz, M., Gayer-Anderson, C., Gomes, FV., Haut, K., Hori, H., Kantrowitz, JT., Kishimoto, T., Lee, FHF., Lin, A., Palaniyappan, L., Quan, M., Rubio, MD., de Azúa, SR., Sahoo, S., Strauss, GP., Szczepankiewicz, A., Thompson, AD., Trotta, A., Tully, LM., Uchida, H., Velthorst, E., Young, JW., O'Shea, A. and DeLisi, LE., (2012). The 3rd Schizophrenia International Research Society Conference, 14–18 April 2012, Florence, Italy: Summaries of oral sessions. Schizophrenia Research. 141 (1), e1-e24

Reports and Papers (1)

Vassos, E., Sham, P., Kempton, M., Trotta, A., Stilo, SA., Gayer-Anderson, C., Forti, MD., Lewis, CM., Murray, RM. and Morgan, C., The Maudsley Environmental Risk Score for Psychosis